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1848
Shozo Akazawa, the 5th head of the family, obtains a certificate granting him permission from the government to deal in medicines, and starts business
Governmental certificate giving permission to deal in medicines
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1883
Chutaro Akazawa obtains a license to operate a pharmacy
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1892
Permission to sell “rodent repellant” obtained, marking the beginning of the business in the field
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1918
“Teikoku Seiyaku Co., Ltd.” established with capital of 1 million yen
Company banner used around the time of Teikoku Seiyaku’s foundation
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1926
“Chemical Cat”, yellow phosphorous-based rodent poison, launched
Signboard for early product called “Chemical Cat”
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1938
“Horxis®”, a prototype of the current medicated plaster, launched
Horxis®
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1943
A group of 212 companies in Kagawa Prefecture join together to establish “Kagawa Prefecture Pharmaceutical Co., Ltd”. and Chutaro Akazawa is appointed as the first president
1848~1948
1949〜1988
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1953
Osaka Plant established in Higashi-yodogawa-ku (now Yodogawa-ku), Osaka
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1957
Osaka Plant spun off as “Fuso Chemical Co., Ltd.” and Shozo Akazawa is appointed president
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1974
Teikoku Seiyaku’s medicated plasters approved for prescription use, becoming the company’s main product line
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1975
First stage of new production plant for plasters (former Plant No.1) completed
Products manufactured, 1975
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1984
Nine-story pharmaceutical development laboratory (now Administration Bldg.) completed at the site of headquarters complex
Development laboratory
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1985
“Teikoku Kampo Seiyaku Co., Ltd”. established New Shirotori Plant completed in Shirotori-cho (now Minato, Higashikagawa), Kagawa Prefecture
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1986
Teikoku Seiyaku acquires stock in Ohta Pharmaceutical Co., Ltd. and starts participating in management
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1988
“Catlep®”, Japan’s first transdermal indomethacin plaster for prescription use, approved and production begins
New plant (now Plant No.2), 5 stories and 6,451 square meters, completed at the site of headquarters complex
1989〜1998
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1989
Distribution Center completed in Shirotori-cho (now Minato, Higashikagawa), Kagawa Prefecture
Shirotori Distribution Center
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1991
Company contributed to the Department of Pharmaco-Bio-Informatics, established at Kagawa Medical University (now Faculty of Medicine, Kagawa University)
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1992
Sales division spun off as an independent company, “Teikoku Medix Co., Ltd.”
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1993
Construction of Plant No.4 dedicated to manufacture of tapes and ointment completed
Ikeda Plant dedicated to manufacture of rodent poison begins operations in Ikeda-cho (now Miyoshi), Tokushima Prefecture (Transferred to Ikeda Yakusou Co., Ltd.)
“Seltouch®”, a transdermal felbinac plaster for prescription use, approved and production begins -
1994
Production begins at Tokushima Plant (Teikoku Kampo Seiyaku Co., Ltd.)
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1995
Non-prescription drug division (OTC) spun off as an independent company, “Teikoku Pharmacare Co., Ltd.”
Teikoku Seiyaku joins the Japan Pharmaceutical Manufacturers Association -
1997
Site of the former Sanbonmatsu Plant of Toyobo Co., Ltd., adjacent to Teikoku Seiyaku headquarters, acquired
US subsidiary, “Teikoku Pharma USA, Inc.”, established
Land adjacent to Tokushima Plant acquired and Donari Plant dedicated to manufacture of cosmetics and related products begins operations -
1998
150th anniversary of the founding of the business and 80th anniversary of the establishment of the company celebrated “Sogyo 150-Nen Shi” (History of the First 150 Years) published
Symbol of the 150th Anniversary
1999〜2008
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1999
“Lidoderm®”, the analgesic plaster for the treatment of post-herpetic neuralgia, approved and launched in the US
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2000
“Dovonex® ointment” for the treatment of psoriasis vulgaris approved and launched(Transferred to LEO Pharma K.K. in 2014)
Construction of Plant No.8 completed at the site of former Toyobo Co., Ltd. and production beginsPlant No.8
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2001
A morphine sulfate sustained-release capsule approved and production begins Production begins at new Plant No.7
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2003
“Fuso Teiyaku Qingdao Co., Ltd.”, established as a joint company by Teikoku Seiyaku Co., Ltd., Fuso Chemical Co., Ltd. and Qingdao Fuso Refining & Processing Co., Ltd.
New pharmacology building completed -
2004
Teikoku Pharma USA, Inc. moves into a new building with a new manufacturing plant
Teikoku Pharma USA, Inc.
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2006
“Omneed® Ketoprofen Patch”, the first OTC ketoprofen patch in Japan, launched by Teikoku Pharmacare Co., Ltd.
Tokyo Office moves into Teikoku’s own building in Nihonbashi-honcho
Formulation research building completed at the site of Sanbonmatsu PlantNew Formulation Research Building
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2007
Teikoku Seiyaku Memorial Gallery, Akazawa Memorial Gallery and Guest House "FUTAGOJIMA" completed
Teikoku Seiyaku Memorial Gallery
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2008
160th anniversary of the founding of the business and 90th anniversary of the establishment of the company celebrated Teikoku Medix Co., Ltd. sold
2009〜
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2009
Construction of a new warehouse completed next to the Tokushima warehouse
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2010
“Seltouch® Tape 70”, a felbinac tape for prescription use, approved and marketing begins in 2011
“Catlep® Tape 70mg” and “Catlep® Tape 35mg”, indomethacin tapes for prescription use, approved and marketing begins -
2011
Capital reduced to 100 million yen
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2012
A methadone hydrochloride tablet, approved and marketing begins in 2013
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2013
A fentanyl citrate buccal tablet co-developed with Taiho Pharmaceutical Co.,Ltd., approved and marketing begins
A oxycodone hydrochloride sustained-release capsule approved and marketing begins in 2014 -
2014
Established Drug & Medical Device Sales Division to sell medicinal products and started to sell Catlep, Inteban, Drenison of Sumitomo Dainippon Pharma based on the distribution right
Completion of Plant No. 9Plant No. 9
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2015
Tokyo Office moved to Ogura Building located in Nihonbashi-kobunacho
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2016
Opened Higashi-Nihon Logistics Center in Higashi-Nihon MDC of Hitachi Logistics
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2017
Awarded a Medal of Honor(the Medal with Dark Blue Ribbon)
Launch RUPAFIN® 10 mg upon NDA approval
Completion of Plant No. 10 to manufacture ointment and creamPlant No. 10
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2018
Celebrated the one hundred and seventieth anniversary since foundation of the company and the one hundredth anniversary since incorporation
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2019
Seren Pharmaceuticals, Inc. becomes an affiliated company of Teikoku Seiyaku
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2020
Teikoku Seiyaku makes the Japanese Ministry of Economy, Trade and Industry’s 2020 Global Niche Top Companies Selection 100 List Receives Eruboshi certification. Eruboshi is awarded by the Ministry of Health, Labour and Welfare to employers who promote the participation and advancement of women in the workplace
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2022
Acquired manufacturing and marketing approval for Japan’s first Donepezil transdermal therapeutic system. ALLYDONE® 27.5 mg patches and ALLYDONE® 55 mg patches go on the market the following year
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2023
Achieves Kurumin mark certification as a childcare supportive organization