1848 Shozo Akazawa, the 5th head of the family, obtains a certificate granting him permission from the government to deal in medicines, and starts business
Governmental certificate giving
permission to deal in medicines
1883 Chutaro Akazawa obtains a license to operate a pharmacy
‘Honzo-zufu’, a botanical encyclopedia
from the time of Akazawa-Yakkan
(trade name)
1892 Permission to sell “rodent repellant” obtained, marking the beginning of the business in the field
1918 “Teikoku Seiyaku Co., Ltd.” established with capital of 1 million yen
Plant at the time of establishment
1926 “Chemical Cat”, yellow phosphorous-based rodent poison, launched
Drugs, circa 1920
Caps and bags
of company peddlers,
circa 1925
1938 “Horxis®”, a prototype of the current medicated plaster, launched
1943 A group of 212 companies in Kagawa Prefecture join together to establish “Kagawa Prefecture Pharmaceutical Co., Ltd”. and Chutaro Akazawa is appointed as the first president
1953 Osaka Plant established in Higashi-yodogawa-ku (now Yodogawa-ku), Osaka
1957 Osaka Plant spun off as “Fuso Chemical Co., Ltd.” and Shozo Akazawa is appointed president
1974 Teikoku Seiyaku’s medicated plasters approved for prescription use, becoming the company’s main product line
1975 First stage of new production plant for plasters (former Plant No.1) completed
Final stage of construction completed in 1978
Products manufactured, 1975
1984 Nine-story pharmaceutical development laboratory (now Administration Bldg.) completed at the site of headquarters complex
Development laboratory
1985 “Teikoku Kampo Seiyaku Co., Ltd”. established
New Shirotori Plant completed in Shirotori-cho (now Minato, Higashikagawa), Kagawa Prefecture
1986 Teikoku Seiyaku acquires stock in Ohta Pharmaceutical Co., Ltd. and starts participating in management
1988 “Catlep®”, Japan’s first transdermal indomethacin plaster for prescription use, approved and production begins
New plant (now Plant No.2), 5 stories and 6,451 square meters, completed at the site of headquarters complex
Catlep
New plant at time of
completion (Now Plant No.2)
1989 Distribution Center completed in Shirotori-cho (now Minato, Higashikagawa), Kagawa Prefecture
Shirotori Distribution Center
1991 Company contributed to the Department of Pharmaco-Bio-Informatics, established at Kagawa Medical University (now Faculty of Medicine, Kagawa University)
1992 Sales division spun off as an independent company, “Teikoku Medix Co., Ltd.”
1993 Construction of Plant No.4 dedicated to manufacture of tapes and ointment completed
Ikeda Plant dedicated to manufacture of rodent poison begins operations in Ikeda-cho (now Miyoshi), Tokushima Prefecture (Transferred to Ikeda Yakusou Co., Ltd.)
“Seltouch®”, a transdermal felbinac plaster for prescription use, approved and production begins
1994 Production begins at Tokushima Plant (Teikoku Kampo Seiyaku Co., Ltd.)
Tokushima Plant
1995 Non-prescription drug division (OTC) spun off as an independent company, “Teikoku Pharmacare Co., Ltd.”
Teikoku Seiyaku joins the Japan Pharmaceutical Manufacturers Association
1997 Site of the former Sanbonmatsu Plant of Toyobo Co., Ltd., adjacent to Teikoku Seiyaku headquarters, acquired
US subsidiary, “Teikoku Pharma USA, Inc.”, established
Land adjacent to Tokushima Plant acquired and Donari Plant dedicated to manufacture of cosmetics and related products begins operations
1998 150th anniversary of the founding of the business and 80th anniversary of the establishment of the company celebrated
“Sogyo 150-Nen Shi” (History of the First 150 Years) published
Symbol of the 150th Anniversary
1999 “Lidoderm®”, the analgesic plaster for the treatment of post-herpetic neuralgia, approved and launched in the US
2000 “Dovonex® ointment” for the treatment of psoriasis vulgaris approved and launched(Transferred to LEO Pharma K.K. in 2014)
Construction of Plant No.8 completed at the site of former Toyobo Co., Ltd. and production begins
2001 A morphine sulfate sustained-release capsule approved and production begins
Production begins at new Plant No.7
2003 “Fuso Teiyaku Qingdao Co., Ltd.”, established as a joint company by Teikoku Seiyaku Co., Ltd., Fuso Chemical Co., Ltd. and Qingdao Fuso Refining & Processing Co., Ltd.
New pharmacology building completed
2004 Teikoku Pharma USA, Inc. moves into a new building with a new manufacturing plant
Teikoku Pharma USA, Inc.
2006 Formulation research building completed at the site of Sanbonmatsu Plant
“Omneed® Ketoprofen Patch”, the first OTC ketoprofen patch in Japan, launched by Teikoku Pharmacare Co., Ltd.
Tokyo Office moves into Teikoku’s own building in Nihonbashi-honcho
2007 Teikoku Seiyaku Memorial Gallery, Akazawa Memorial Gallery and Guest House "FUTAGOJIMA" completed
Teikoku Seiyaku
Memorial Gallery
Guest House
"FUTAGOJIMA"
2008 160th anniversary of the founding of the business and 90th anniversary of the establishment of the company celebrated
Teikoku Medix Co., Ltd. sold
2009 Construction of a new warehouse completed next to the Tokushima warehouse
2010 “Seltouch® Tape 70”, a felbinac tape for prescription use, approved and marketing begins in 2011
“Catlep® Tape 70mg” and “Catlep® Tape 35mg”, indomethacin tapes for prescription use, approved and marketing begins
2011 Capital reduced to 100 million yen
2012 A methadone hydrochloride tablet, approved and marketing begins in 2013
2013 A fentanyl citrate buccal tablet co-developed with Taiho Pharmaceutical Co.,Ltd., approved and marketing begins
A oxycodone hydrochloride sustained-release capsule approved and marketing begins in 2014
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